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A boronic acid is an organic compound related to boric acid (B(OH)3) in which one of the three hydroxyl groups (−OH) is replaced by an alkyl or aryl group (represented by R in the general formula R−B(OH)2). As a compound containing a carbon–boron bond, members of this class thus belong to the larger class of。 See more

Optimizing the compatibility of boronic acids for MCR is an interesting synthetic challenge, as the C─B bond is well known to react with common MCR starting materials and intermediates under mild conditions,。

Boron containing compounds have not been widely studied in Medicinal Chemistry, mainly due to the idea that this group could confer some toxicity. Nowadays, this concept has been demystified and, especially after the。

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